A simple method for testing the efficacy of a .BETA.-lactamase inhibitor against .BETA.-lactamase-producing gram-negative bacteria.
نویسندگان
چکیده
منابع مشابه
Comparative in vitro activity of beta-lactam/beta-lactamase inhibitor combinations against gram negative bacteria.
BACKGROUND & OBJECTIVE Currently, the use of beta-lactamase inhibitors in combination with beta-lactam antibiotics represents an effective measure to combat a specific resistance mechanism of beta-lactamase producing organisms. Knowledge about the susceptibility profile of bacteria to different combination agents available is essential to guide appropriate treatment of severe infections in hosp...
متن کاملScreening of Extended Spectrum Beta lactamase Producing Gram Negative Bacilli Isolated from Clinical Cases
Abstract Background and objectives: (ESBL) strain is one of the emerging health related problems in the world recently. Some of the species of the gram-negative bacilli including Klebsiella Pneumonia & Escherichia Coli are well known ESBL producing among bacteria, and they cause uncontrollable infections. This Cross-sectional study was designed to asses the ESBL producing gra...
متن کاملExtended-spectrum Beta-lactamase Producing Gram Negative Bacteria in Iran: a Review
BACKGROUND The emergence and spread of extended spectrum β-lactamase (ESBL)-producing Gram- negative bacteria (GNB), particularly in Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa, have increased all over the world. ESBLs are characterized by their ability to hydrolyze β-lactams, early cephalosporins, oxyimino-thiazolyl cephalosporins, and monobactams, but not cephamyci...
متن کاملA comparative in vitro study of cephalosporin/beta-lactamase inhibitor combinations against gram negative bacilli.
The present study aims at comparing the in-vitro susceptibility of six commercially available cephalosporin--BLI combinations with cephalosporins alone against hospital isolates of Gram negative bacilli. Gram negative bacilli, numbering 500, isolated from various clinical samples, were included in the study. The isolates were also screened for ESBL production by the methods recommended by CLSI....
متن کاملActivity of beta-lactam beta-lactamase inhibitor combinations against extended spectrum Beta-lactamase producing Enterobacteriaceae in urinary isolates.
OBJECTIVE To determine the susceptibility pattern of beta-lactam beta-lactamase inhibitor combinations against extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae in urinary isolates. STUDY DESIGN Observational study. PLACE AND DURATION OF STUDY Ziauddin University Hospital, Karachi, from February to October 2008. METHODOLOGY A total of 190 consecutive non-duplicate isola...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1982
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.35.1072